diff --git a/crates/ruff_linter/src/rules/ruff/snapshots/ruff_linter__rules__ruff__tests__range_suppressions.snap b/crates/ruff_linter/src/rules/ruff/snapshots/ruff_linter__rules__ruff__tests__range_suppressions.snap
index 24a43ade5e..908cca2cbd 100644
--- a/crates/ruff_linter/src/rules/ruff/snapshots/ruff_linter__rules__ruff__tests__range_suppressions.snap
+++ b/crates/ruff_linter/src/rules/ruff/snapshots/ruff_linter__rules__ruff__tests__range_suppressions.snap
@@ -7,7 +7,7 @@ source: crates/ruff_linter/src/rules/ruff/mod.rs
 
 --- Summary ---
 Removed: 14
-Added: 11
+Added: 18
 
 --- Removed ---
 E741 Ambiguous variable name: `I`
@@ -240,6 +240,17 @@ note: This is an unsafe fix and may change runtime behavior
 
 
 --- Added ---
+RUF104 Unmatched suppression comment
+  --> suppressions.py:11:5
+   |
+ 9 |     # These should both be ignored by the implicit range suppression.
+10 |     # Should also generate an "unmatched suppression" warning.
+11 |     # ruff:disable[E741,F841]
+   |     ^^^^^^^^^^^^^^^^^^^^^^^^^
+12 |     I = 1
+   |
+
+
 RUF100 [*] Unused suppression (non-enabled: `E501`)
   --> suppressions.py:46:5
    |
@@ -298,6 +309,17 @@ help: Remove unused `noqa` directive
 58 | 
 
 
+RUF104 Unmatched suppression comment
+  --> suppressions.py:61:5
+   |
+59 | def f():
+60 |     # TODO: Duplicate codes should be counted as duplicate, not unused
+61 |     # ruff: disable[F841, F841]
+   |     ^^^^^^^^^^^^^^^^^^^^^^^^^^^
+62 |     foo = 0
+   |
+
+
 RUF100 [*] Unused suppression (unused: `F841`)
   --> suppressions.py:61:21
    |
@@ -318,6 +340,18 @@ help: Remove unused suppression
 64 | 
 
 
+RUF104 Unmatched suppression comment
+  --> suppressions.py:68:5
+   |
+66 |     # Overlapping range suppressions, one should be marked as used,
+67 |     # and the other should trigger an unused suppression diagnostic
+68 |     # ruff: disable[F841]
+   |     ^^^^^^^^^^^^^^^^^^^^^
+69 |     # ruff: disable[F841]
+70 |     foo = 0
+   |
+
+
 RUF100 [*] Unused suppression (unused: `F841`)
   --> suppressions.py:69:5
    |
@@ -337,6 +371,28 @@ help: Remove unused suppression
 71 | 
 
 
+RUF104 Unmatched suppression comment
+  --> suppressions.py:69:5
+   |
+67 |     # and the other should trigger an unused suppression diagnostic
+68 |     # ruff: disable[F841]
+69 |     # ruff: disable[F841]
+   |     ^^^^^^^^^^^^^^^^^^^^^
+70 |     foo = 0
+   |
+
+
+RUF104 Unmatched suppression comment
+  --> suppressions.py:75:5
+   |
+73 | def f():
+74 |     # Multiple codes but only one is used
+75 |     # ruff: disable[E741, F401, F841]
+   |     ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+76 |     foo = 0
+   |
+
+
 RUF100 [*] Unused suppression (unused: `E741`)
   --> suppressions.py:75:21
    |
@@ -377,6 +433,17 @@ help: Remove unused suppression
 78 | 
 
 
+RUF104 Unmatched suppression comment
+  --> suppressions.py:81:5
+   |
+79 | def f():
+80 |     # Multiple codes but only two are used
+81 |     # ruff: disable[E741, F401, F841]
+   |     ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+82 |     I = 0
+   |
+
+
 RUF100 [*] Unused suppression (non-enabled: `F401`)
   --> suppressions.py:81:27
    |
@@ -397,6 +464,17 @@ help: Remove unused suppression
 84 | 
 
 
+RUF104 Unmatched suppression comment
+  --> suppressions.py:87:5
+   |
+85 | def f():
+86 |     # Multiple codes but none are used
+87 |     # ruff: disable[E741, F401, F841]
+   |     ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+88 |     print("hello")
+   |
+
+
 RUF100 [*] Unused suppression (unused: `E741`)
   --> suppressions.py:87:21
    |
diff --git a/crates/ruff_linter/src/suppression.rs b/crates/ruff_linter/src/suppression.rs
index 18c6ad50ce..7b4e57a67a 100644
--- a/crates/ruff_linter/src/suppression.rs
+++ b/crates/ruff_linter/src/suppression.rs
@@ -4,6 +4,7 @@ use ruff_db::diagnostic::Diagnostic;
 use ruff_diagnostics::{Edit, Fix};
 use ruff_python_ast::token::{TokenKind, Tokens};
 use ruff_python_ast::whitespace::indentation;
+use rustc_hash::FxHashSet;
 use std::cell::Cell;
 use std::{error::Error, fmt::Formatter};
 use thiserror::Error;
@@ -17,7 +18,9 @@ use crate::checkers::ast::LintContext;
 use crate::codes::Rule;
 use crate::fix::edits::delete_comment;
 use crate::preview::is_range_suppressions_enabled;
-use crate::rules::ruff::rules::{UnusedCodes, UnusedNOQA, UnusedNOQAKind};
+use crate::rules::ruff::rules::{
+    UnmatchedSuppressionComment, UnusedCodes, UnusedNOQA, UnusedNOQAKind,
+};
 use crate::settings::LinterSettings;
 
 #[derive(Clone, Debug, Eq, PartialEq)]
@@ -220,6 +223,19 @@ impl Suppressions {
             }
         }
 
+        let unmatched = self
+            .valid
+            .iter()
+            .filter(|suppression| {
+                suppression.comments.len() == 1
+                    && suppression.comments[0].action == SuppressionAction::Disable
+            })
+            .map(|suppression| suppression.comments[0].range)
+            .collect::<FxHashSet<TextRange>>();
+        for range in unmatched {
+            context.report_diagnostic(UnmatchedSuppressionComment {}, range);
+        }
+
         for error in self
             .errors
             .iter()