diff --git a/crates/ruff_linter/resources/test/fixtures/flake8_type_checking/TC006.py b/crates/ruff_linter/resources/test/fixtures/flake8_type_checking/TC006.py
index cf10553c49..a321f2a30e 100644
--- a/crates/ruff_linter/resources/test/fixtures/flake8_type_checking/TC006.py
+++ b/crates/ruff_linter/resources/test/fixtures/flake8_type_checking/TC006.py
@@ -89,3 +89,11 @@ def f():
         int  # TC006
         , 6.0
     )
+
+
+def f():
+    # Keyword arguments
+    from typing import cast
+
+    cast(typ=int, val=3.0)  # TC006
+    cast(val=3.0, typ=int)  # TC006
diff --git a/crates/ruff_linter/src/checkers/ast/mod.rs b/crates/ruff_linter/src/checkers/ast/mod.rs
index ebff124383..10784403e4 100644
--- a/crates/ruff_linter/src/checkers/ast/mod.rs
+++ b/crates/ruff_linter/src/checkers/ast/mod.rs
@@ -1539,25 +1539,37 @@ impl<'a> Visitor<'a> for Checker<'a> {
                         }
                     }
                     Some(typing::Callable::Cast) => {
-                        let mut args = arguments.args.iter();
-                        if let Some(arg) = args.next() {
-                            self.visit_type_definition(arg);
-
-                            if !self.source_type.is_stub() && self.enabled(Rule::RuntimeCastValue) {
-                                flake8_type_checking::rules::runtime_cast_value(self, arg);
+                        for (i, arg) in arguments.arguments_source_order().enumerate() {
+                            match (i, arg) {
+                                (0, ArgOrKeyword::Arg(arg)) => self.visit_cast_type_argument(arg),
+                                (_, ArgOrKeyword::Arg(arg)) => self.visit_non_type_definition(arg),
+                                (_, ArgOrKeyword::Keyword(Keyword { arg, value, .. })) => {
+                                    if let Some(id) = arg {
+                                        if id == "typ" {
+                                            self.visit_cast_type_argument(value);
+                                        } else {
+                                            self.visit_non_type_definition(value);
+                                        }
+                                    }
+                                }
                             }
                         }
-                        for arg in args {
-                            self.visit_expr(arg);
-                        }
                     }
                     Some(typing::Callable::NewType) => {
-                        let mut args = arguments.args.iter();
-                        if let Some(arg) = args.next() {
-                            self.visit_non_type_definition(arg);
-                        }
-                        for arg in args {
-                            self.visit_type_definition(arg);
+                        for (i, arg) in arguments.arguments_source_order().enumerate() {
+                            match (i, arg) {
+                                (1, ArgOrKeyword::Arg(arg)) => self.visit_type_definition(arg),
+                                (_, ArgOrKeyword::Arg(arg)) => self.visit_non_type_definition(arg),
+                                (_, ArgOrKeyword::Keyword(Keyword { arg, value, .. })) => {
+                                    if let Some(id) = arg {
+                                        if id == "tp" {
+                                            self.visit_type_definition(value);
+                                        } else {
+                                            self.visit_non_type_definition(value);
+                                        }
+                                    }
+                                }
+                            }
                         }
                     }
                     Some(typing::Callable::TypeVar) => {
@@ -2209,6 +2221,15 @@ impl<'a> Checker<'a> {
         self.semantic.flags = snapshot;
     }
 
+    /// Visit an [`Expr`], and treat it as the `typ` argument to `typing.cast`.
+    fn visit_cast_type_argument(&mut self, arg: &'a Expr) {
+        self.visit_type_definition(arg);
+
+        if !self.source_type.is_stub() && self.enabled(Rule::RuntimeCastValue) {
+            flake8_type_checking::rules::runtime_cast_value(self, arg);
+        }
+    }
+
     /// Visit an [`Expr`], and treat it as a boolean test. This is useful for detecting whether an
     /// expressions return value is significant, or whether the calling context only relies on
     /// its truthiness.
diff --git a/crates/ruff_linter/src/rules/flake8_type_checking/snapshots/ruff_linter__rules__flake8_type_checking__tests__runtime-cast-value_TC006.py.snap b/crates/ruff_linter/src/rules/flake8_type_checking/snapshots/ruff_linter__rules__flake8_type_checking__tests__runtime-cast-value_TC006.py.snap
index 25348b34ab..f117c364f7 100644
--- a/crates/ruff_linter/src/rules/flake8_type_checking/snapshots/ruff_linter__rules__flake8_type_checking__tests__runtime-cast-value_TC006.py.snap
+++ b/crates/ruff_linter/src/rules/flake8_type_checking/snapshots/ruff_linter__rules__flake8_type_checking__tests__runtime-cast-value_TC006.py.snap
@@ -212,3 +212,37 @@ TC006.py:89:9: TC006 [*] Add quotes to type expression in `typing.cast()`
    89 |+        "int"  # TC006
 90 90 |         , 6.0
 91 91 |     )
+92 92 | 
+
+TC006.py:98:14: TC006 [*] Add quotes to type expression in `typing.cast()`
+   |
+96 |     from typing import cast
+97 |
+98 |     cast(typ=int, val=3.0)  # TC006
+   |              ^^^ TC006
+99 |     cast(val=3.0, typ=int)  # TC006
+   |
+   = help: Add quotes
+
+ℹ Safe fix
+95 95 |     # Keyword arguments
+96 96 |     from typing import cast
+97 97 | 
+98    |-    cast(typ=int, val=3.0)  # TC006
+   98 |+    cast(typ="int", val=3.0)  # TC006
+99 99 |     cast(val=3.0, typ=int)  # TC006
+
+TC006.py:99:23: TC006 [*] Add quotes to type expression in `typing.cast()`
+   |
+98 |     cast(typ=int, val=3.0)  # TC006
+99 |     cast(val=3.0, typ=int)  # TC006
+   |                       ^^^ TC006
+   |
+   = help: Add quotes
+
+ℹ Safe fix
+96 96 |     from typing import cast
+97 97 | 
+98 98 |     cast(typ=int, val=3.0)  # TC006
+99    |-    cast(val=3.0, typ=int)  # TC006
+   99 |+    cast(val=3.0, typ="int")  # TC006