diff --git a/crates/uv/tests/common/mod.rs b/crates/uv/tests/common/mod.rs
index 0a1ea9a4f..d255a7c26 100644
--- a/crates/uv/tests/common/mod.rs
+++ b/crates/uv/tests/common/mod.rs
@@ -1118,7 +1118,7 @@ pub fn make_project(dir: &Path, name: &str, body: &str) -> anyhow::Result<()> {
         {body}
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         "#
diff --git a/crates/uv/tests/edit.rs b/crates/uv/tests/edit.rs
index 930ba3ed7..3d3235ba2 100644
--- a/crates/uv/tests/edit.rs
+++ b/crates/uv/tests/edit.rs
@@ -25,7 +25,7 @@ fn add_registry() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -60,7 +60,7 @@ fn add_registry() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -152,7 +152,7 @@ fn add_git() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -224,7 +224,7 @@ fn add_git() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -330,7 +330,7 @@ fn add_git_private_source() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -363,7 +363,7 @@ fn add_git_private_source() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -434,7 +434,7 @@ fn add_git_private_raw() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -472,7 +472,7 @@ fn add_git_private_raw() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -537,7 +537,7 @@ fn add_git_error() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -599,7 +599,7 @@ fn add_git_raw() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -658,7 +658,7 @@ fn add_git_raw() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -759,7 +759,7 @@ fn add_git_implicit() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -819,7 +819,7 @@ fn add_raw_error() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -855,7 +855,7 @@ fn add_unnamed() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -888,7 +888,7 @@ fn add_unnamed() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -956,7 +956,7 @@ fn add_remove_dev() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -989,7 +989,7 @@ fn add_remove_dev() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -1115,7 +1115,7 @@ fn add_remove_dev() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -1172,7 +1172,7 @@ fn add_remove_optional() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -1210,7 +1210,7 @@ fn add_remove_optional() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -1333,7 +1333,7 @@ fn add_remove_optional() -> Result<()> {
         io = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -1389,7 +1389,7 @@ fn add_remove_inline_optional() -> Result<()> {
         ] }
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -1422,7 +1422,7 @@ fn add_remove_inline_optional() -> Result<()> {
         ] }
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -1460,7 +1460,7 @@ fn add_remove_inline_optional() -> Result<()> {
         ], types = [] }
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -1489,7 +1489,7 @@ fn add_remove_workspace() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -1502,7 +1502,7 @@ fn add_remove_workspace() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -1560,7 +1560,7 @@ fn add_remove_workspace() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -1647,7 +1647,7 @@ fn add_remove_workspace() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -1720,7 +1720,7 @@ fn add_workspace_editable() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -1733,7 +1733,7 @@ fn add_workspace_editable() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -1770,7 +1770,7 @@ fn add_workspace_editable() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -1845,7 +1845,7 @@ fn add_path() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -1858,7 +1858,7 @@ fn add_path() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -1893,7 +1893,7 @@ fn add_path() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -1963,7 +1963,7 @@ fn update() -> Result<()> {
         dependencies = ["requests==2.31.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -2022,7 +2022,7 @@ fn update() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2061,7 +2061,7 @@ fn update() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2101,7 +2101,7 @@ fn update() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -2255,7 +2255,7 @@ fn add_update_marker() -> Result<()> {
         dependencies = ["requests>=2.30; python_version >= '3.11'"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     uv_snapshot!(context.filters(), context.lock(), @r###"
@@ -2315,7 +2315,7 @@ fn add_update_marker() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2353,7 +2353,7 @@ fn add_update_marker() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2396,7 +2396,7 @@ fn add_update_marker() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2437,7 +2437,7 @@ fn add_update_marker() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2477,7 +2477,7 @@ fn add_update_marker() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2502,7 +2502,7 @@ fn update_source_replace_url() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -2540,7 +2540,7 @@ fn update_source_replace_url() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -2566,7 +2566,7 @@ fn add_inexact() -> Result<()> {
         dependencies = ["anyio == 3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -2602,7 +2602,7 @@ fn add_inexact() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -2636,7 +2636,7 @@ fn add_inexact() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2718,7 +2718,7 @@ fn remove_registry() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -2775,7 +2775,7 @@ fn remove_registry() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2828,7 +2828,7 @@ fn add_preserves_indentation_in_pyproject_toml() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -2868,7 +2868,7 @@ fn add_preserves_indentation_in_pyproject_toml() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2889,7 +2889,7 @@ fn add_puts_default_indentation_in_pyproject_toml_if_not_observed() -> Result<()
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -2929,7 +2929,7 @@ fn add_puts_default_indentation_in_pyproject_toml_if_not_observed() -> Result<()
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -2951,7 +2951,7 @@ fn add_frozen() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -2979,7 +2979,7 @@ fn add_frozen() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -3004,7 +3004,7 @@ fn add_no_sync() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3033,7 +3033,7 @@ fn add_no_sync() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -3126,7 +3126,7 @@ fn add_error() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3169,7 +3169,7 @@ fn add_lower_bound() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3205,7 +3205,7 @@ fn add_lower_bound() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -3228,7 +3228,7 @@ fn add_lower_bound_existing() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3265,7 +3265,7 @@ fn add_lower_bound_existing() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -3288,7 +3288,7 @@ fn add_lower_bound_raw() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3324,7 +3324,7 @@ fn add_lower_bound_raw() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -3347,7 +3347,7 @@ fn add_lower_bound_dev() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3381,7 +3381,7 @@ fn add_lower_bound_dev() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -3409,7 +3409,7 @@ fn add_lower_bound_optional() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3448,7 +3448,7 @@ fn add_lower_bound_optional() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -3531,7 +3531,7 @@ fn add_lower_bound_local() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3565,7 +3565,7 @@ fn add_lower_bound_local() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -3716,7 +3716,7 @@ fn add_repeat() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3751,7 +3751,7 @@ fn add_repeat() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -3783,7 +3783,7 @@ fn add_repeat() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
@@ -3806,7 +3806,7 @@ fn add_requirements_file() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -3853,7 +3853,7 @@ fn add_requirements_file() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -4351,7 +4351,7 @@ fn fail_to_add_revert_project() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -4402,7 +4402,7 @@ fn fail_to_add_revert_project() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "###
         );
diff --git a/crates/uv/tests/export.rs b/crates/uv/tests/export.rs
index 084395443..bab185aea 100644
--- a/crates/uv/tests/export.rs
+++ b/crates/uv/tests/export.rs
@@ -23,7 +23,7 @@ fn dependency() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -67,7 +67,7 @@ fn dependency_extra() -> Result<()> {
         dependencies = ["flask[dotenv]"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -142,7 +142,7 @@ fn project_extra() -> Result<()> {
         pytest = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -223,7 +223,7 @@ fn dependency_marker() -> Result<()> {
         dependencies = ["anyio ; sys_platform == 'darwin'", "iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -273,7 +273,7 @@ fn dependency_multiple_markers() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -370,7 +370,7 @@ fn dependency_conflicting_markers() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -449,7 +449,7 @@ fn non_root() -> Result<()> {
         child = { workspace = true }
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -464,7 +464,7 @@ fn non_root() -> Result<()> {
         dependencies = ["iniconfig>=2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -502,7 +502,7 @@ fn relative_path() -> Result<()> {
         dependencies = ["iniconfig>=2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -520,7 +520,7 @@ fn relative_path() -> Result<()> {
         dependency = { path = "../dependency" }
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -586,7 +586,7 @@ fn dev() -> Result<()> {
         dev-dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
diff --git a/crates/uv/tests/lock.rs b/crates/uv/tests/lock.rs
index edde5dd37..a263d2439 100644
--- a/crates/uv/tests/lock.rs
+++ b/crates/uv/tests/lock.rs
@@ -30,7 +30,7 @@ fn lock_wheel_registry() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -156,7 +156,7 @@ fn lock_sdist_registry() -> Result<()> {
         dependencies = ["source-distribution==0.0.1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -242,7 +242,7 @@ fn lock_sdist_git() -> Result<()> {
         dependencies = ["uv-public-pypackage"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -336,7 +336,7 @@ fn lock_sdist_git() -> Result<()> {
         dependencies = ["uv-public-pypackage"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -396,7 +396,7 @@ fn lock_sdist_git() -> Result<()> {
         dependencies = ["uv-public-pypackage"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -456,7 +456,7 @@ fn lock_sdist_git() -> Result<()> {
         dependencies = ["uv-public-pypackage"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -524,7 +524,7 @@ fn lock_sdist_git_subdirectory() -> Result<()> {
         dependencies = ["example-pkg-a @ git+https://github.com/pypa/sample-namespace-packages.git@df7530eeb8fa0cb7dbb8ecb28363e8e36bfa2f45#subdirectory=pkg_resources/pkg_a"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -612,7 +612,7 @@ fn lock_sdist_git_pep508() -> Result<()> {
         dependencies = ["uv-public-pypackage @ git+https://github.com/astral-test/uv-public-pypackage.git@0.0.1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -679,7 +679,7 @@ fn lock_sdist_git_pep508() -> Result<()> {
         dependencies = ["uv-public-pypackage @ git+https://github.com/astral-test/uv-public-pypackage.git@0dacfd662c64cb4ceb16e6cf65a157a8b715b979"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -736,7 +736,7 @@ fn lock_sdist_git_pep508() -> Result<()> {
         dependencies = ["uv-public-pypackage @ git+https://github.com/astral-test/uv-public-pypackage.git@b270df1a2fb5d012294e9aaf05e7e0bab1e6a389"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -793,7 +793,7 @@ fn lock_sdist_git_pep508() -> Result<()> {
         dependencies = ["uv-public-pypackage @ git+https://github.com/astral-test/uv-public-pypackage.git@0.0.2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -858,7 +858,7 @@ fn lock_sdist_git_short_rev() -> Result<()> {
         dependencies = ["uv-public-pypackage"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -959,7 +959,7 @@ fn lock_wheel_url() -> Result<()> {
         dependencies = ["anyio @ https://files.pythonhosted.org/packages/14/fd/2f20c40b45e4fb4324834aea24bd4afdf1143390242c0b33774da0e2e34f/anyio-4.3.0-py3-none-any.whl"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -1106,7 +1106,7 @@ fn lock_sdist_url() -> Result<()> {
         dependencies = ["anyio @ https://files.pythonhosted.org/packages/db/4d/3970183622f0330d3c23d9b8a5f52e365e50381fd484d08e3285104333d3/anyio-4.3.0.tar.gz"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -1240,7 +1240,7 @@ fn lock_project_extra() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [project.optional-dependencies]
@@ -1386,7 +1386,7 @@ fn lock_project_with_overrides() -> Result<()> {
         dependencies = ["flask==3.0.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -1450,7 +1450,7 @@ fn lock_project_with_constraints() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -1510,7 +1510,7 @@ fn lock_dependency_extra() -> Result<()> {
         dependencies = ["flask[dotenv]"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -1710,7 +1710,7 @@ fn lock_conditional_dependency_extra() -> Result<()> {
         dependencies = ["requests", "requests[socks] ; python_version < '3.10'"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -1996,7 +1996,7 @@ fn lock_dependency_non_existent_extra() -> Result<()> {
         dependencies = ["flask[foo]"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2182,7 +2182,7 @@ fn lock_upgrade_log() -> Result<()> {
         dependencies = ["markupsafe<2", "iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2263,7 +2263,7 @@ fn lock_upgrade_log() -> Result<()> {
         dependencies = ["markupsafe", "typing-extensions"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2358,7 +2358,7 @@ fn lock_upgrade_log_multi_version() -> Result<()> {
         dependencies = ["markupsafe<2 ; sys_platform != 'win32'", "markupsafe==2.0.0 ; sys_platform == 'win32'"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2445,7 +2445,7 @@ fn lock_upgrade_log_multi_version() -> Result<()> {
         dependencies = ["markupsafe"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2524,7 +2524,7 @@ fn lock_preference() -> Result<()> {
         dependencies = ["iniconfig<2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2584,7 +2584,7 @@ fn lock_preference() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2703,7 +2703,7 @@ fn lock_git_sha() -> Result<()> {
         dependencies = ["uv-public-pypackage @ git+https://github.com/astral-test/uv-public-pypackage@main"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2746,7 +2746,7 @@ fn lock_git_sha() -> Result<()> {
         dependencies = ["uv-public-pypackage @ git+https://github.com/astral-test/uv-public-pypackage@main"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2826,7 +2826,7 @@ fn lock_requires_python() -> Result<()> {
         dependencies = ["pygls>=1.1.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -2866,7 +2866,7 @@ fn lock_requires_python() -> Result<()> {
         dependencies = ["pygls"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -3021,7 +3021,7 @@ fn lock_requires_python() -> Result<()> {
         dependencies = ["pygls"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -3166,7 +3166,7 @@ fn lock_requires_python() -> Result<()> {
         dependencies = ["pygls"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -3311,7 +3311,7 @@ fn lock_requires_python_upper() -> Result<()> {
         dependencies = ["pydantic"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -3462,7 +3462,7 @@ fn lock_requires_python_wheels() -> Result<()> {
         dependencies = ["frozenlist"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -3549,7 +3549,7 @@ fn lock_requires_python_wheels() -> Result<()> {
         dependencies = ["frozenlist"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -3662,7 +3662,7 @@ fn lock_requires_python_star() -> Result<()> {
         dependencies = ["linehaul"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -3788,7 +3788,7 @@ fn lock_requires_python_pre() -> Result<()> {
         dependencies = ["linehaul"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -3912,7 +3912,7 @@ fn lock_requires_python_unbounded() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -4007,7 +4007,7 @@ fn lock_python_version_marker_complement() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -4121,7 +4121,7 @@ fn lock_dev() -> Result<()> {
         dev-dependencies = ["typing-extensions @ https://files.pythonhosted.org/packages/26/9f/ad63fc0248c5379346306f8668cda6e2e2e9c95e01216d2b8ffd9ff037d0/typing_extensions-4.12.2-py3-none-any.whl"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -4239,7 +4239,7 @@ fn lock_conditional_unconditional() -> Result<()> {
         dependencies = ["iniconfig", "iniconfig ; python_version < '3.12'"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -4320,7 +4320,7 @@ fn lock_multiple_markers() -> Result<()> {
         dependencies = ["iniconfig ; implementation_name == 'cpython'", "iniconfig ; python_version < '3.12'"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -4404,7 +4404,7 @@ fn lock_relative_and_absolute_paths() -> Result<()> {
         c = {{ path = '{}' }}
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
         context.temp_dir.join("c").display()
@@ -4422,7 +4422,7 @@ fn lock_relative_and_absolute_paths() -> Result<()> {
         license = {text = "MIT"}
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
     "#})?;
@@ -4439,7 +4439,7 @@ fn lock_relative_and_absolute_paths() -> Result<()> {
         license = {text = "MIT"}
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
     "#})?;
@@ -4523,7 +4523,7 @@ fn lock_cycles() -> Result<()> {
         dependencies = ["testtools==2.3.0", "fixtures==3.0.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -4730,7 +4730,7 @@ fn lock_new_extras() -> Result<()> {
         dependencies = ["requests==2.31.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
     "#,
@@ -4858,7 +4858,7 @@ fn lock_new_extras() -> Result<()> {
         dependencies = ["requests[socks]==2.31.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
     "#,
@@ -5011,7 +5011,7 @@ fn lock_invalid_hash() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -5111,7 +5111,7 @@ fn lock_resolution_mode() -> Result<()> {
         dependencies = ["anyio>=3"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -5293,7 +5293,7 @@ fn lock_requires_python_no_wheels() -> Result<()> {
         dependencies = ["dearpygui==1.9.1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -5329,7 +5329,7 @@ fn lock_same_version_multiple_urls() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -5346,7 +5346,7 @@ fn lock_same_version_multiple_urls() -> Result<()> {
         dependencies = ["anyio==3.0.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -5364,7 +5364,7 @@ fn lock_same_version_multiple_urls() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
         Url::from_file_path(context.temp_dir.join("v1")).unwrap(),
@@ -5526,7 +5526,7 @@ fn lock_unsafe_lowest() -> Result<()> {
         all = ["project[dev]"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -5568,7 +5568,7 @@ fn lock_exclusion() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -5590,7 +5590,7 @@ fn lock_exclusion() -> Result<()> {
         dependencies = ["project"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -5675,7 +5675,7 @@ fn lock_dev_transitive() -> Result<()> {
         dev-dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -5693,7 +5693,7 @@ fn lock_dev_transitive() -> Result<()> {
         dependencies = ["foo", "baz", "iniconfig>1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -5718,7 +5718,7 @@ fn lock_dev_transitive() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -5846,7 +5846,7 @@ fn lock_redact_https() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -5995,7 +5995,7 @@ fn lock_redact_https() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -6042,7 +6042,7 @@ fn lock_redact_git() -> Result<()> {
         dependencies = ["uv-private-pypackage @ git+https://{token}@github.com/astral-test/uv-private-pypackage"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
         token = token,
@@ -6130,7 +6130,7 @@ fn lock_relative_index() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -6224,7 +6224,7 @@ fn lock_no_sources() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -6245,7 +6245,7 @@ fn lock_no_sources() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -6417,7 +6417,7 @@ fn lock_migrate() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -6563,7 +6563,7 @@ fn lock_upgrade_package() -> Result<()> {
         dependencies = ["anyio<=2", "idna<=3"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -6661,7 +6661,7 @@ fn lock_upgrade_package() -> Result<()> {
         dependencies = ["anyio", "idna"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -6893,7 +6893,7 @@ fn lock_warn_missing_transitive_lower_bounds() -> Result<()> {
         dependencies = ["pytest>8"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -6948,7 +6948,7 @@ fn lock_find_links_local_wheel() -> Result<()> {
         dependencies = ["tqdm==1000.0.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -7066,7 +7066,7 @@ fn lock_find_links_local_sdist() -> Result<()> {
         dependencies = ["tqdm==999.0.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -7161,7 +7161,7 @@ fn lock_find_links_http_wheel() -> Result<()> {
         dependencies = ["packaging==23.2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -7256,7 +7256,7 @@ fn lock_find_links_http_sdist() -> Result<()> {
         dependencies = ["packaging==23.2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -7386,7 +7386,7 @@ fn lock_local_index() -> Result<()> {
         dependencies = ["tqdm"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -7487,7 +7487,7 @@ fn lock_sources_url() -> Result<()> {
         dependencies = ["workspace @ https://github.com/user-attachments/files/16592193/workspace.zip"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -7626,7 +7626,7 @@ fn lock_sources_archive() -> Result<()> {
         dependencies = ["workspace @ {}"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
         Url::from_file_path(&workspace_archive).unwrap(),
@@ -7879,7 +7879,7 @@ fn lock_editable() -> Result<()> {
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -7899,7 +7899,7 @@ fn lock_editable() -> Result<()> {
         dependencies = ["library"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -7916,7 +7916,7 @@ fn lock_editable() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     library.child("src/__init__.py").touch()?;
@@ -7998,7 +7998,7 @@ fn lock_editable() -> Result<()> {
         dependencies = ["library"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -8105,7 +8105,7 @@ fn lock_mixed_extras() -> Result<()> {
         dependencies = ["leaf1", "workspace2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [project.optional-dependencies]
@@ -8132,7 +8132,7 @@ fn lock_mixed_extras() -> Result<()> {
         async = ["iniconfig>=2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     leaf1.child("src/__init__.py").touch()?;
@@ -8147,7 +8147,7 @@ fn lock_mixed_extras() -> Result<()> {
         dependencies = ["leaf2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -8170,7 +8170,7 @@ fn lock_mixed_extras() -> Result<()> {
         async = ["packaging>=24"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     leaf2.child("src/__init__.py").touch()?;
@@ -8341,7 +8341,7 @@ fn lock_transitive_extra() -> Result<()> {
         dependencies = ["leaf"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [project.optional-dependencies]
@@ -8368,7 +8368,7 @@ fn lock_transitive_extra() -> Result<()> {
         async = ["iniconfig>=2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     leaf.child("src/__init__.py").touch()?;
@@ -8556,7 +8556,7 @@ fn lock_mismatched_versions() -> Result<()> {
         dependencies = ["uv-public-pypackage==0.0.2"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -8650,7 +8650,7 @@ fn unconditional_overlapping_marker_disjoint_version_constraints() -> Result<()>
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -8683,7 +8683,7 @@ fn lock_change_index() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -8809,7 +8809,7 @@ fn lock_remove_member() -> Result<()> {
         dependencies = ["anyio>3"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -8824,7 +8824,7 @@ fn lock_remove_member() -> Result<()> {
         dependencies = ["leaf"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -9009,7 +9009,7 @@ fn lock_add_member() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -9068,7 +9068,7 @@ fn lock_add_member() -> Result<()> {
         dependencies = ["anyio>3"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -9083,7 +9083,7 @@ fn lock_add_member() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -9230,7 +9230,7 @@ fn lock_redundant_add_member() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -9325,7 +9325,7 @@ fn lock_redundant_add_member() -> Result<()> {
         dependencies = ["anyio", "idna"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -9436,7 +9436,7 @@ fn lock_new_constraints() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -9528,7 +9528,7 @@ fn lock_new_constraints() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -9638,7 +9638,7 @@ fn lock_remove_member_non_project() -> Result<()> {
         members = ["leaf"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -9654,7 +9654,7 @@ fn lock_remove_member_non_project() -> Result<()> {
         dependencies = ["anyio>3"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -9812,7 +9812,7 @@ fn lock_rename_project() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -9882,7 +9882,7 @@ fn lock_rename_project() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -9964,7 +9964,7 @@ fn lock_missing_metadata() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -10106,7 +10106,7 @@ fn lock_reorder() -> Result<()> {
         dependencies = ["anyio", "iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -10211,7 +10211,7 @@ fn lock_reorder() -> Result<()> {
         dependencies = ["iniconfig", "anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -10243,7 +10243,7 @@ fn lock_narrowed_python_version() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -10258,7 +10258,7 @@ fn lock_narrowed_python_version() -> Result<()> {
         dependencies = ["dependency ; python_version < '3.9'", "dependency ; python_version > '3.10'"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -10365,7 +10365,7 @@ fn lock_exclude_unnecessary_python_forks() -> Result<()> {
             "anyio ; python_version > '3.10'"
         ]
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -10472,7 +10472,7 @@ fn lock_constrained_environment() -> Result<()> {
         dependencies = ["black"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -10620,7 +10620,7 @@ fn lock_constrained_environment() -> Result<()> {
         dependencies = ["black"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -10649,7 +10649,7 @@ fn lock_constrained_environment() -> Result<()> {
         dependencies = ["black"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -10800,7 +10800,7 @@ fn lock_overlapping_environment() -> Result<()> {
         dependencies = ["black"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -11131,7 +11131,7 @@ fn lock_dropped_dev_extra() -> Result<()> {
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -11249,7 +11249,7 @@ fn lock_trailing_slash() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -11378,7 +11378,7 @@ fn lock_explicit_virtual_project() -> Result<()> {
         dependencies = ["black"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -11977,7 +11977,7 @@ fn lock_conflicting_environment() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
diff --git a/crates/uv/tests/pip_compile.rs b/crates/uv/tests/pip_compile.rs
index 0f62f4de9..1d92e28b0 100644
--- a/crates/uv/tests/pip_compile.rs
+++ b/crates/uv/tests/pip_compile.rs
@@ -152,7 +152,7 @@ fn compile_pyproject_toml() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -193,7 +193,7 @@ fn compile_pyproject_toml_dynamic_version() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -233,7 +233,7 @@ fn compile_pyproject_toml_with_line_annotation() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -423,7 +423,7 @@ fn compile_pyproject_toml_extra() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -466,7 +466,7 @@ fn compile_pyproject_toml_extra_name_normalization() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -509,7 +509,7 @@ fn compile_pyproject_toml_extra_missing() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -877,7 +877,7 @@ fn compile_pyproject_toml_invalid_name() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "!project"
@@ -914,7 +914,7 @@ fn compile_pyproject_toml_extras_missing() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -976,7 +976,7 @@ fn invalid_extra_name() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -2296,7 +2296,7 @@ fn compile_pyproject_toml_all_extras() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -2352,7 +2352,7 @@ fn compile_pyproject_toml_all_extras_annotation_line() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -2399,7 +2399,7 @@ fn compile_does_not_allow_both_extra_and_all_extras() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "project"
@@ -2442,7 +2442,7 @@ fn compile_unsolvable_requirements() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "my-project"
@@ -2474,7 +2474,7 @@ fn compile_unsolvable_requirements_version_not_available() -> Result<()> {
     let pyproject_toml = context.temp_dir.child("pyproject.toml");
     pyproject_toml.write_str(
         r#"[build-system]
-requires = ["setuptools", "wheel"]
+requires = ["setuptools>=42"]
 
 [project]
 name = "my-project"
diff --git a/crates/uv/tests/run.rs b/crates/uv/tests/run.rs
index 462b7beb7..5300ed4b8 100644
--- a/crates/uv/tests/run.rs
+++ b/crates/uv/tests/run.rs
@@ -29,7 +29,7 @@ fn run_with_python_version() -> Result<()> {
         ]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -152,7 +152,7 @@ fn run_args() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -211,7 +211,7 @@ fn run_pep723_script() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -463,7 +463,7 @@ fn run_pythonw_script() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -576,7 +576,7 @@ fn run_managed_false() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -609,7 +609,7 @@ fn run_with() -> Result<()> {
         dependencies = ["anyio", "sniffio==1.3.1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -709,7 +709,7 @@ fn run_with_editable() -> Result<()> {
         dependencies = ["anyio", "sniffio==1.3.1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -775,7 +775,7 @@ fn run_with_editable() -> Result<()> {
         dependencies = ["anyio", "sniffio==1.3.1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -839,7 +839,7 @@ fn run_locked() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -869,7 +869,7 @@ fn run_locked() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -925,7 +925,7 @@ fn run_frozen() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -952,7 +952,7 @@ fn run_frozen() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -989,7 +989,7 @@ fn run_empty_requirements_txt() -> Result<()> {
         dependencies = ["anyio", "sniffio==1.3.1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -1049,7 +1049,7 @@ fn run_requirements_txt() -> Result<()> {
         dependencies = ["anyio", "sniffio==1.3.1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -1168,7 +1168,7 @@ fn run_requirements_txt_arguments() -> Result<()> {
         dependencies = ["typing_extensions"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -1222,7 +1222,7 @@ fn run_editable() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -1284,7 +1284,7 @@ fn run_from_directory() -> Result<()> {
         main = "main:main"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -1332,7 +1332,7 @@ fn run_without_output() -> Result<()> {
         dependencies = ["anyio", "sniffio==1.3.1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -1380,7 +1380,7 @@ fn run_isolated_python_version() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -1479,7 +1479,7 @@ fn run_no_project() -> Result<()> {
         dependencies = ["anyio"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
@@ -1631,7 +1631,7 @@ fn run_isolated_incompatible_python() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#
     })?;
diff --git a/crates/uv/tests/sync.rs b/crates/uv/tests/sync.rs
index a2354c832..85d60a95e 100644
--- a/crates/uv/tests/sync.rs
+++ b/crates/uv/tests/sync.rs
@@ -23,7 +23,7 @@ fn sync() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -61,7 +61,7 @@ fn locked() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -91,7 +91,7 @@ fn locked() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -129,7 +129,7 @@ fn frozen() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -156,7 +156,7 @@ fn frozen() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -235,7 +235,7 @@ fn package() -> Result<()> {
         dependencies = ["child", "anyio>3"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -265,7 +265,7 @@ fn package() -> Result<()> {
         dependencies = ["iniconfig>1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -344,7 +344,7 @@ fn mixed_requires_python() -> Result<()> {
         requires-python = ">=3.8"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -417,7 +417,7 @@ fn virtual_workspace_dev_dependencies() -> Result<()> {
         dependencies = ["iniconfig>1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -481,7 +481,7 @@ fn sync_build_isolation() -> Result<()> {
         dependencies = ["source-distribution @ https://files.pythonhosted.org/packages/10/1f/57aa4cce1b1abf6b433106676e15f9fa2c92ed2bd4cf77c3b50a9e9ac773/source_distribution-0.0.1.tar.gz"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -920,7 +920,7 @@ fn sync_environment() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -964,7 +964,7 @@ fn read_metadata_statically_over_the_cache() -> Result<()> {
         dependencies = ["anyio>=4,<5"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -997,7 +997,7 @@ fn no_install_project() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -1051,7 +1051,7 @@ fn no_install_workspace() -> Result<()> {
         dependencies = ["anyio==3.7.0", "child"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -1073,7 +1073,7 @@ fn no_install_workspace() -> Result<()> {
         dependencies = ["iniconfig>1"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -1165,7 +1165,7 @@ fn no_install_package() -> Result<()> {
         dependencies = ["anyio==3.7.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -1222,7 +1222,7 @@ fn convert_to_virtual() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
@@ -1414,7 +1414,7 @@ fn convert_to_package() -> Result<()> {
         dependencies = ["iniconfig"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
         "#,
     )?;
diff --git a/crates/uv/tests/workspace.rs b/crates/uv/tests/workspace.rs
index eac9d7e17..97e7c8cad 100644
--- a/crates/uv/tests/workspace.rs
+++ b/crates/uv/tests/workspace.rs
@@ -1026,7 +1026,7 @@ fn workspace_inherit_sources() -> Result<()> {
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -1043,7 +1043,7 @@ fn workspace_inherit_sources() -> Result<()> {
         dependencies = ["library"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     leaf.child("src/__init__.py").touch()?;
@@ -1057,7 +1057,7 @@ fn workspace_inherit_sources() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     library.child("src/__init__.py").touch()?;
@@ -1086,7 +1086,7 @@ fn workspace_inherit_sources() -> Result<()> {
         dependencies = ["library"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -1114,7 +1114,7 @@ fn workspace_inherit_sources() -> Result<()> {
         dependencies = ["library"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
 
@@ -1127,7 +1127,7 @@ fn workspace_inherit_sources() -> Result<()> {
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -1202,7 +1202,7 @@ fn workspace_inherit_sources() -> Result<()> {
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -1220,7 +1220,7 @@ fn workspace_inherit_sources() -> Result<()> {
         dependencies = ["library"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.sources]
@@ -1259,7 +1259,7 @@ fn workspace_unsatisfiable_member_dependencies() -> Result<()> {
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -1276,7 +1276,7 @@ fn workspace_unsatisfiable_member_dependencies() -> Result<()> {
         dependencies = ["httpx>9999"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     leaf.child("src/__init__.py").touch()?;
@@ -1315,7 +1315,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting() -> Result<()> {
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -1332,7 +1332,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting() -> Result<()> {
         dependencies = ["anyio==4.1.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     foo.child("src/__init__.py").touch()?;
@@ -1344,7 +1344,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting() -> Result<()> {
         dependencies = ["anyio==4.2.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     bar.child("src/__init__.py").touch()?;
@@ -1383,7 +1383,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_threeway() -> Result<
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -1400,7 +1400,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_threeway() -> Result<
         dependencies = ["anyio==4.1.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     red.child("src/__init__.py").touch()?;
@@ -1412,7 +1412,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_threeway() -> Result<
         dependencies = ["anyio==4.2.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     knot.child("src/__init__.py").touch()?;
@@ -1427,7 +1427,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_threeway() -> Result<
         dependencies = ["anyio==4.3.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     bird.child("src/__init__.py").touch()?;
@@ -1466,7 +1466,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_extra() -> Result<()>
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -1483,7 +1483,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_extra() -> Result<()>
         dependencies = ["anyio==4.1.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     foo.child("src/__init__.py").touch()?;
@@ -1497,7 +1497,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_extra() -> Result<()>
         some_extra = ["anyio==4.2.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     bar.child("src/__init__.py").touch()?;
@@ -1536,7 +1536,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_dev() -> Result<()> {
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -1553,7 +1553,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_dev() -> Result<()> {
         dependencies = ["anyio==4.1.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     foo.child("src/__init__.py").touch()?;
@@ -1564,7 +1564,7 @@ fn workspace_unsatisfiable_member_dependencies_conflicting_dev() -> Result<()> {
         version = "0.1.0"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv]
@@ -1607,7 +1607,7 @@ fn workspace_member_name_shadows_dependencies() -> Result<()> {
         requires-python = ">=3.12"
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
 
         [tool.uv.workspace]
@@ -1624,7 +1624,7 @@ fn workspace_member_name_shadows_dependencies() -> Result<()> {
         dependencies = ["anyio==4.1.0"]
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     foo.child("src/__init__.py").touch()?;
@@ -1638,7 +1638,7 @@ fn workspace_member_name_shadows_dependencies() -> Result<()> {
         dependencies = []
 
         [build-system]
-        requires = ["setuptools>=42", "wheel"]
+        requires = ["setuptools>=42"]
         build-backend = "setuptools.build_meta"
     "#})?;
     anyio.child("src/__init__.py").touch()?;