diff --git a/Cargo.lock b/Cargo.lock
index 86855115f..486f5e160 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -5097,7 +5097,6 @@ dependencies = [
  "which",
  "whoami",
  "windows 0.59.0",
- "windows-result",
  "wiremock",
  "zip",
 ]
@@ -5711,7 +5710,6 @@ dependencies = [
  "tokio",
  "tracing",
  "windows 0.59.0",
- "windows-core 0.59.0",
 ]
 
 [[package]]
@@ -5858,7 +5856,7 @@ dependencies = [
  "security-framework",
  "thiserror 2.0.16",
  "tokio",
- "windows-sys 0.59.0",
+ "windows 0.59.0",
  "zeroize",
 ]
 
@@ -6144,9 +6142,8 @@ dependencies = [
  "uv-trampoline-builder",
  "uv-warnings",
  "which",
+ "windows 0.59.0",
  "windows-registry",
- "windows-result",
- "windows-sys 0.59.0",
 ]
 
 [[package]]
@@ -6357,9 +6354,8 @@ dependencies = [
  "tracing",
  "uv-fs",
  "uv-static",
+ "windows 0.59.0",
  "windows-registry",
- "windows-result",
- "windows-sys 0.59.0",
 ]
 
 [[package]]
diff --git a/Cargo.toml b/Cargo.toml
index 75ebd6a5e..d52099ae0 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -195,11 +195,8 @@ uuid = { version = "1.16.0" }
 version-ranges = { git = "https://github.com/astral-sh/pubgrub", rev = "06ec5a5f59ffaeb6cf5079c6cb184467da06c9db" }
 walkdir = { version = "2.5.0" }
 which = { version = "8.0.0", features = ["regex"] }
-windows = { version = "0.59.0", features = ["Win32_Globalization", "Win32_System_Console", "Win32_System_Kernel", "Win32_System_Diagnostics_Debug", "Win32_Storage_FileSystem"] }
-windows-core = { version = "0.59.0" }
+windows = { version = "0.59.0", features = ["Win32_Globalization", "Win32_Security", "Win32_System_Console", "Win32_System_Kernel", "Win32_System_Diagnostics_Debug", "Win32_Storage_FileSystem", "Win32_System_Registry", "Win32_System_IO", "Win32_System_Ioctl"] }
 windows-registry = { version = "0.5.0" }
-windows-result = { version = "0.3.0" }
-windows-sys = { version = "0.59.0", features = ["Win32_Foundation", "Win32_Security", "Win32_Storage_FileSystem", "Win32_System_Ioctl", "Win32_System_IO", "Win32_System_Registry"] }
 wiremock = { version = "0.6.4" }
 xz2 = { version = "0.1.7" }
 zeroize = { version = "1.8.1" }
diff --git a/crates/uv-fs/Cargo.toml b/crates/uv-fs/Cargo.toml
index fba4910e6..a9ac2126d 100644
--- a/crates/uv-fs/Cargo.toml
+++ b/crates/uv-fs/Cargo.toml
@@ -37,7 +37,6 @@ rustix = { workspace = true }
 backon = { workspace = true }
 junction = { workspace = true }
 windows = { workspace = true }
-windows-core = { workspace = true }
 
 [features]
 default = []
diff --git a/crates/uv-fs/src/which.rs b/crates/uv-fs/src/which.rs
index e63174a17..403f17a3e 100644
--- a/crates/uv-fs/src/which.rs
+++ b/crates/uv-fs/src/which.rs
@@ -5,7 +5,7 @@ use std::path::Path;
 fn get_binary_type(path: &Path) -> windows::core::Result<u32> {
     use std::os::windows::ffi::OsStrExt;
     use windows::Win32::Storage::FileSystem::GetBinaryTypeW;
-    use windows_core::PCWSTR;
+    use windows::core::PCWSTR;
 
     // References:
     // https://github.com/denoland/deno/blob/01a6379505712be34ebf2cdc874fa7f54a6e9408/runtime/permissions/which.rs#L131-L154
diff --git a/crates/uv-keyring/Cargo.toml b/crates/uv-keyring/Cargo.toml
index 27d333891..90b5ef35d 100644
--- a/crates/uv-keyring/Cargo.toml
+++ b/crates/uv-keyring/Cargo.toml
@@ -18,7 +18,7 @@ apple-native = ["dep:security-framework"]
 ## Use the secret-service on *nix.
 secret-service = ["dep:secret-service"]
 ## Use the built-in credential store on Windows
-windows-native = ["dep:windows-sys", "dep:byteorder"]
+windows-native = ["dep:windows", "dep:byteorder"]
 
 [dependencies]
 async-trait = { workspace = true }
@@ -33,7 +33,7 @@ secret-service = { workspace = true, features = ["rt-tokio-crypto-rust"], option
 
 [target.'cfg(target_os = "windows")'.dependencies]
 byteorder = { workspace = true, optional = true }
-windows-sys = { workspace = true, features = ["Win32_Foundation", "Win32_Security_Credentials"], optional = true }
+windows = { workspace = true, features = ["Win32_Foundation", "Win32_Security_Credentials"], optional = true }
 zeroize = { workspace = true }
 
 [dev-dependencies]
diff --git a/crates/uv-keyring/src/windows.rs b/crates/uv-keyring/src/windows.rs
index eb644f650..30c8d918a 100644
--- a/crates/uv-keyring/src/windows.rs
+++ b/crates/uv-keyring/src/windows.rs
@@ -44,15 +44,16 @@ use byteorder::{ByteOrder, LittleEndian};
 use std::collections::HashMap;
 use std::iter::once;
 use std::str;
-use windows_sys::Win32::Foundation::{
+use windows::Win32::Foundation::{
     ERROR_BAD_USERNAME, ERROR_INVALID_FLAGS, ERROR_INVALID_PARAMETER, ERROR_NO_SUCH_LOGON_SESSION,
-    ERROR_NOT_FOUND, FILETIME, GetLastError,
+    ERROR_NOT_FOUND, FILETIME, WIN32_ERROR,
 };
-use windows_sys::Win32::Security::Credentials::{
+use windows::Win32::Security::Credentials::{
     CRED_FLAGS, CRED_MAX_CREDENTIAL_BLOB_SIZE, CRED_MAX_GENERIC_TARGET_NAME_LENGTH,
     CRED_MAX_STRING_LENGTH, CRED_MAX_USERNAME_LENGTH, CRED_PERSIST_ENTERPRISE, CRED_TYPE_GENERIC,
     CREDENTIAL_ATTRIBUTEW, CREDENTIALW, CredDeleteW, CredFree, CredReadW, CredWriteW,
 };
+use windows::core::PWSTR;
 use zeroize::Zeroize;
 
 /// The representation of a Windows Generic credential.
@@ -160,15 +161,13 @@ impl CredentialApi for WinCredential {
     /// credential in the store.
     async fn delete_credential(&self) -> Result<()> {
         self.validate_attributes(None, None)?;
-        let target_name = to_wstr(&self.target_name);
+        let mut target_name = to_wstr(&self.target_name);
         let cred_type = CRED_TYPE_GENERIC;
         crate::blocking::spawn_blocking(move || {
             // SAFETY: Calling Windows API
-            if unsafe { CredDeleteW(target_name.as_ptr(), cred_type, 0) } != 0 {
-                Ok(())
-            } else {
-                // SAFETY: Calling Windows API
-                Err(Error::from_win32_code(unsafe { GetLastError() }).into())
+            unsafe {
+                CredDeleteW(PWSTR(target_name.as_mut_ptr()), cred_type, None)
+                    .map_err(|err| Error(err).into())
             }
         })
         .await
@@ -264,22 +263,20 @@ impl WinCredential {
             let credential = CREDENTIALW {
                 Flags: flags,
                 Type: cred_type,
-                TargetName: target_name.as_mut_ptr(),
-                Comment: comment.as_mut_ptr(),
+                TargetName: PWSTR(target_name.as_mut_ptr()),
+                Comment: PWSTR(comment.as_mut_ptr()),
                 LastWritten: last_written,
                 CredentialBlobSize: blob_len,
                 CredentialBlob: blob.as_mut_ptr(),
                 Persist: persist,
                 AttributeCount: attribute_count,
                 Attributes: attributes,
-                TargetAlias: target_alias.as_mut_ptr(),
-                UserName: username.as_mut_ptr(),
+                TargetAlias: PWSTR(target_alias.as_mut_ptr()),
+                UserName: PWSTR(username.as_mut_ptr()),
             };
             // SAFETY: Calling Windows API
-            let result = match unsafe { CredWriteW(&raw const credential, 0) } {
-                0 => Err(Error::from_win32_code(unsafe { GetLastError() }).into()),
-                _ => Ok(()),
-            };
+            let result =
+                unsafe { CredWriteW(&raw const credential, 0) }.map_err(|err| Error(err).into());
             // erase the copy of the secret
             blob.zeroize();
             result
@@ -300,31 +297,33 @@ impl WinCredential {
         T: Send + 'static,
     {
         self.validate_attributes(None, None)?;
-        let target_name = to_wstr(&self.target_name);
+        let mut target_name = to_wstr(&self.target_name);
         crate::blocking::spawn_blocking(move || {
             let mut p_credential = std::ptr::null_mut();
             // at this point, p_credential is just a pointer to nowhere.
             // The allocation happens in the `CredReadW` call below.
             let cred_type = CRED_TYPE_GENERIC;
             // SAFETY: Calling windows API
-            let result =
-                unsafe { CredReadW(target_name.as_ptr(), cred_type, 0, &raw mut p_credential) };
-            if result == 0 {
-                // `CredReadW` failed, so no allocation has been done, so no free needs to be done
-                Err(Error::from_win32_code(unsafe { GetLastError() }).into())
-            } else {
-                // SAFETY: `CredReadW` succeeded, so p_credential points at an allocated credential. Apply
-                // the passed extractor function to it.
-                let ref_cred: &mut CREDENTIALW = unsafe { &mut *p_credential };
-                let result = f(ref_cred);
-                // Finally, we erase the secret and free the allocated credential.
-                erase_secret(ref_cred);
-                let p_credential = p_credential;
-                // SAFETY: `CredReadW` succeeded, so p_credential points at an allocated credential.
-                // Free the allocation.
-                unsafe { CredFree(p_credential.cast()) }
-                result
+            unsafe {
+                CredReadW(
+                    PWSTR(target_name.as_mut_ptr()),
+                    cred_type,
+                    None,
+                    &raw mut p_credential,
+                )
             }
+            .map_err(Error)?;
+            // SAFETY: `CredReadW` succeeded, so p_credential points at an allocated credential. Apply
+            // the passed extractor function to it.
+            let ref_cred: &mut CREDENTIALW = unsafe { &mut *p_credential };
+            let result = f(ref_cred);
+            // Finally, we erase the secret and free the allocated credential.
+            erase_secret(ref_cred);
+            let p_credential = p_credential;
+            // SAFETY: `CredReadW` succeeded, so p_credential points at an allocated credential.
+            // Free the allocation.
+            unsafe { CredFree(p_credential.cast()) }
+            result
         })
         .await
     }
@@ -332,10 +331,10 @@ impl WinCredential {
     #[allow(clippy::unnecessary_wraps)]
     fn extract_credential(w_credential: &CREDENTIALW) -> Result<Self> {
         Ok(Self {
-            username: unsafe { from_wstr(w_credential.UserName) },
-            target_name: unsafe { from_wstr(w_credential.TargetName) },
-            target_alias: unsafe { from_wstr(w_credential.TargetAlias) },
-            comment: unsafe { from_wstr(w_credential.Comment) },
+            username: unsafe { from_wstr(w_credential.UserName.as_ptr()) },
+            target_name: unsafe { from_wstr(w_credential.TargetName.as_ptr()) },
+            target_alias: unsafe { from_wstr(w_credential.TargetAlias.as_ptr()) },
+            comment: unsafe { from_wstr(w_credential.Comment.as_ptr()) },
         })
     }
 
@@ -475,34 +474,40 @@ unsafe fn from_wstr(ws: *const u16) -> String {
 
 /// Windows error codes are `DWORDS` which are 32-bit unsigned ints.
 #[derive(Debug)]
-pub struct Error(pub u32);
+pub struct Error(windows::core::Error);
 
-impl Error {
-    /// Create a Windows error from a Win32 error code.
-    pub fn from_win32_code(code: u32) -> Self {
-        Self(code)
+impl From<WIN32_ERROR> for Error {
+    fn from(error: WIN32_ERROR) -> Self {
+        Self(windows::core::Error::from(error))
     }
 }
 
 impl From<Error> for ErrorCode {
     fn from(err: Error) -> Self {
-        match err.0 {
-            ERROR_NOT_FOUND => Self::NoEntry,
-            ERROR_NO_SUCH_LOGON_SESSION => Self::NoStorageAccess(Box::new(err)),
-            _ => Self::PlatformFailure(Box::new(err)),
+        if err.0 == ERROR_NOT_FOUND.into() {
+            Self::NoEntry
+        } else if err.0 == ERROR_NO_SUCH_LOGON_SESSION.into() {
+            Self::NoStorageAccess(Box::new(err))
+        } else {
+            Self::PlatformFailure(Box::new(err))
         }
     }
 }
 
 impl std::fmt::Display for Error {
     fn fmt(&self, f: &mut std::fmt::Formatter) -> std::fmt::Result {
-        match self.0 {
-            ERROR_NO_SUCH_LOGON_SESSION => write!(f, "Windows ERROR_NO_SUCH_LOGON_SESSION"),
-            ERROR_NOT_FOUND => write!(f, "Windows ERROR_NOT_FOUND"),
-            ERROR_BAD_USERNAME => write!(f, "Windows ERROR_BAD_USERNAME"),
-            ERROR_INVALID_FLAGS => write!(f, "Windows ERROR_INVALID_FLAGS"),
-            ERROR_INVALID_PARAMETER => write!(f, "Windows ERROR_INVALID_PARAMETER"),
-            err => write!(f, "Windows error code {err}"),
+        if self.0 == ERROR_NO_SUCH_LOGON_SESSION.into() {
+            write!(f, "Windows ERROR_NO_SUCH_LOGON_SESSION")
+        } else if self.0 == ERROR_NOT_FOUND.into() {
+            write!(f, "Windows ERROR_NOT_FOUND")
+        } else if self.0 == ERROR_BAD_USERNAME.into() {
+            write!(f, "Windows ERROR_BAD_USERNAME")
+        } else if self.0 == ERROR_INVALID_FLAGS.into() {
+            write!(f, "Windows ERROR_INVALID_FLAGS")
+        } else if self.0 == ERROR_INVALID_PARAMETER.into() {
+            write!(f, "Windows ERROR_INVALID_PARAMETER")
+        } else {
+            write!(f, "Windows error code {}", self.0)
         }
     }
 }
@@ -545,18 +550,18 @@ mod tests {
             let attribute_count = 0;
             let attributes: *mut CREDENTIAL_ATTRIBUTEW = std::ptr::null_mut();
             CREDENTIALW {
-                Flags: 0,
+                Flags: CRED_FLAGS(0),
                 Type: CRED_TYPE_GENERIC,
-                TargetName: std::ptr::null_mut(),
-                Comment: std::ptr::null_mut(),
+                TargetName: PWSTR::null(),
+                Comment: PWSTR::null(),
                 LastWritten: last_written,
                 CredentialBlobSize: password.len() as u32,
                 CredentialBlob: password.as_mut_ptr(),
                 Persist: CRED_PERSIST_ENTERPRISE,
                 AttributeCount: attribute_count,
                 Attributes: attributes,
-                TargetAlias: std::ptr::null_mut(),
-                UserName: std::ptr::null_mut(),
+                TargetAlias: PWSTR::null(),
+                UserName: PWSTR::null(),
             }
         }
         // the first malformed sequence can't be UTF-16 because it has an odd number of bytes.
diff --git a/crates/uv-python/Cargo.toml b/crates/uv-python/Cargo.toml
index 4e18d5337..7e48421b8 100644
--- a/crates/uv-python/Cargo.toml
+++ b/crates/uv-python/Cargo.toml
@@ -70,8 +70,7 @@ once_cell = { workspace = true }
 
 [target.'cfg(target_os = "windows")'.dependencies]
 windows-registry = { workspace = true }
-windows-result = { workspace = true }
-windows-sys = { workspace = true }
+windows = { workspace = true }
 
 [dev-dependencies]
 anyhow = { workspace = true }
diff --git a/crates/uv-python/src/discovery.rs b/crates/uv-python/src/discovery.rs
index 217606ae1..218631c75 100644
--- a/crates/uv-python/src/discovery.rs
+++ b/crates/uv-python/src/discovery.rs
@@ -8,9 +8,6 @@ use std::{env, io, iter};
 use std::{path::Path, path::PathBuf, str::FromStr};
 use thiserror::Error;
 use tracing::{debug, instrument, trace};
-use uv_preview::Preview;
-use which::{which, which_all};
-
 use uv_cache::Cache;
 use uv_fs::Simplified;
 use uv_fs::which::is_executable;
@@ -18,8 +15,10 @@ use uv_pep440::{
     LowerBound, Prerelease, UpperBound, Version, VersionSpecifier, VersionSpecifiers,
     release_specifiers_to_ranges,
 };
+use uv_preview::Preview;
 use uv_static::EnvVars;
 use uv_warnings::warn_user_once;
+use which::{which, which_all};
 
 use crate::downloads::{PlatformRequest, PythonDownloadRequest};
 use crate::implementation::ImplementationName;
@@ -251,7 +250,7 @@ pub enum Error {
 
     #[cfg(windows)]
     #[error("Failed to query installed Python versions from the Windows registry")]
-    RegistryError(#[from] windows_result::Error),
+    RegistryError(#[from] windows::core::Error),
 
     /// An invalid version request was given
     #[error("Invalid version request: {0}")]
@@ -1502,13 +1501,15 @@ fn warn_on_unsupported_python(interpreter: &Interpreter) {
 pub(crate) fn is_windows_store_shim(path: &Path) -> bool {
     use std::os::windows::fs::MetadataExt;
     use std::os::windows::prelude::OsStrExt;
-    use windows_sys::Win32::Foundation::{CloseHandle, INVALID_HANDLE_VALUE};
-    use windows_sys::Win32::Storage::FileSystem::{
+    use windows::Win32::Foundation::CloseHandle;
+    use windows::Win32::Storage::FileSystem::{
         CreateFileW, FILE_ATTRIBUTE_REPARSE_POINT, FILE_FLAG_BACKUP_SEMANTICS,
-        FILE_FLAG_OPEN_REPARSE_POINT, MAXIMUM_REPARSE_DATA_BUFFER_SIZE, OPEN_EXISTING,
+        FILE_FLAG_OPEN_REPARSE_POINT, FILE_SHARE_MODE, MAXIMUM_REPARSE_DATA_BUFFER_SIZE,
+        OPEN_EXISTING,
     };
-    use windows_sys::Win32::System::IO::DeviceIoControl;
-    use windows_sys::Win32::System::Ioctl::FSCTL_GET_REPARSE_POINT;
+    use windows::Win32::System::IO::DeviceIoControl;
+    use windows::Win32::System::Ioctl::FSCTL_GET_REPARSE_POINT;
+    use windows::core::PCWSTR;
 
     // The path must be absolute.
     if !path.is_absolute() {
@@ -1553,7 +1554,7 @@ pub(crate) fn is_windows_store_shim(path: &Path) -> bool {
     let Ok(md) = fs_err::symlink_metadata(path) else {
         return false;
     };
-    if md.file_attributes() & FILE_ATTRIBUTE_REPARSE_POINT == 0 {
+    if md.file_attributes() & FILE_ATTRIBUTE_REPARSE_POINT.0 == 0 {
         return false;
     }
 
@@ -1567,19 +1568,19 @@ pub(crate) fn is_windows_store_shim(path: &Path) -> bool {
     #[allow(unsafe_code)]
     let reparse_handle = unsafe {
         CreateFileW(
-            path_encoded.as_mut_ptr(),
+            PCWSTR(path_encoded.as_mut_ptr()),
             0,
-            0,
-            std::ptr::null_mut(),
+            FILE_SHARE_MODE(0),
+            None,
             OPEN_EXISTING,
             FILE_FLAG_BACKUP_SEMANTICS | FILE_FLAG_OPEN_REPARSE_POINT,
-            std::ptr::null_mut(),
+            None,
         )
     };
 
-    if reparse_handle == INVALID_HANDLE_VALUE {
+    let Ok(reparse_handle) = reparse_handle else {
         return false;
-    }
+    };
 
     let mut buf = [0u16; MAXIMUM_REPARSE_DATA_BUFFER_SIZE as usize];
     let mut bytes_returned = 0;
@@ -1590,19 +1591,20 @@ pub(crate) fn is_windows_store_shim(path: &Path) -> bool {
         DeviceIoControl(
             reparse_handle,
             FSCTL_GET_REPARSE_POINT,
-            std::ptr::null_mut(),
+            None,
             0,
-            buf.as_mut_ptr().cast(),
+            Some(buf.as_mut_ptr().cast()),
             buf.len() as u32 * 2,
-            &raw mut bytes_returned,
-            std::ptr::null_mut(),
-        ) != 0
+            Some(&raw mut bytes_returned),
+            None,
+        )
+        .is_ok()
     };
 
     // SAFETY: The handle is valid.
     #[allow(unsafe_code)]
     unsafe {
-        CloseHandle(reparse_handle);
+        let _ = CloseHandle(reparse_handle);
     }
 
     // If the operation failed, assume it's not a reparse point.
diff --git a/crates/uv-python/src/interpreter.rs b/crates/uv-python/src/interpreter.rs
index 8469f05f1..310bf682a 100644
--- a/crates/uv-python/src/interpreter.rs
+++ b/crates/uv-python/src/interpreter.rs
@@ -34,7 +34,7 @@ use crate::{
 };
 
 #[cfg(windows)]
-use windows_sys::Win32::Foundation::{APPMODEL_ERROR_NO_PACKAGE, ERROR_CANT_ACCESS_FILE};
+use windows::Win32::Foundation::{APPMODEL_ERROR_NO_PACKAGE, ERROR_CANT_ACCESS_FILE, WIN32_ERROR};
 
 /// A Python executable and its associated platform markers.
 #[derive(Debug, Clone)]
@@ -928,8 +928,10 @@ impl InterpreterInfo {
                     _ => {}
                 }
                 #[cfg(windows)]
-                if let Some(APPMODEL_ERROR_NO_PACKAGE | ERROR_CANT_ACCESS_FILE) =
-                    err.raw_os_error().and_then(|code| u32::try_from(code).ok())
+                if let Some(APPMODEL_ERROR_NO_PACKAGE | ERROR_CANT_ACCESS_FILE) = err
+                    .raw_os_error()
+                    .and_then(|code| u32::try_from(code).ok())
+                    .map(WIN32_ERROR)
                 {
                     // These error codes are returned if the Python interpreter is a corrupt MSIX
                     // package, which we want to differentiate from a typical spawn failure.
diff --git a/crates/uv-python/src/managed.rs b/crates/uv-python/src/managed.rs
index 6ccba8f45..23dba54fe 100644
--- a/crates/uv-python/src/managed.rs
+++ b/crates/uv-python/src/managed.rs
@@ -15,7 +15,7 @@ use thiserror::Error;
 use tracing::{debug, warn};
 use uv_preview::{Preview, PreviewFeatures};
 #[cfg(windows)]
-use windows_sys::Win32::Storage::FileSystem::FILE_ATTRIBUTE_REPARSE_POINT;
+use windows::Win32::Storage::FileSystem::FILE_ATTRIBUTE_REPARSE_POINT;
 
 use uv_fs::{LockedFile, Simplified, replace_symlink, symlink_or_copy_file};
 use uv_platform::{Error as PlatformError, Os};
@@ -857,7 +857,7 @@ impl PythonMinorVersionLink {
                 .is_ok_and(|metadata| {
                     // Check that this is a reparse point, which indicates this
                     // is a symlink or junction.
-                    (metadata.file_attributes() & FILE_ATTRIBUTE_REPARSE_POINT) != 0
+                    (metadata.file_attributes() & FILE_ATTRIBUTE_REPARSE_POINT.0) != 0
                 })
         }
     }
diff --git a/crates/uv-python/src/windows_registry.rs b/crates/uv-python/src/windows_registry.rs
index cd6393aec..359555153 100644
--- a/crates/uv-python/src/windows_registry.rs
+++ b/crates/uv-python/src/windows_registry.rs
@@ -12,13 +12,10 @@ use thiserror::Error;
 use tracing::debug;
 use uv_platform::Arch;
 use uv_warnings::{warn_user, warn_user_once};
+use windows::Win32::Foundation::ERROR_FILE_NOT_FOUND;
+use windows::Win32::System::Registry::{KEY_WOW64_32KEY, KEY_WOW64_64KEY};
+use windows::core::HRESULT;
 use windows_registry::{CURRENT_USER, HSTRING, Key, LOCAL_MACHINE, Value};
-use windows_result::HRESULT;
-use windows_sys::Win32::Foundation::ERROR_FILE_NOT_FOUND;
-use windows_sys::Win32::System::Registry::{KEY_WOW64_32KEY, KEY_WOW64_64KEY};
-
-/// Code returned when the registry key doesn't exist.
-const ERROR_NOT_FOUND: HRESULT = HRESULT::from_win32(ERROR_FILE_NOT_FOUND);
 
 /// A Python interpreter found in the Windows registry through PEP 514 or from a known Microsoft
 /// Store path.
@@ -32,7 +29,7 @@ pub(crate) struct WindowsPython {
 }
 
 /// Find all Pythons registered in the Windows registry following PEP 514.
-pub(crate) fn registry_pythons() -> Result<Vec<WindowsPython>, windows_result::Error> {
+pub(crate) fn registry_pythons() -> Result<Vec<WindowsPython>, windows::core::Error> {
     let mut registry_pythons = Vec::new();
     // Prefer `HKEY_CURRENT_USER` over `HKEY_LOCAL_MACHINE`.
     // By default, a 64-bit program does not see a 32-bit global (HKLM) installation of Python in
@@ -47,7 +44,7 @@ pub(crate) fn registry_pythons() -> Result<Vec<WindowsPython>, windows_result::E
         let mut open_options = root_key.options();
         open_options.read();
         if let Some(access_modifier) = access_modifier {
-            open_options.access(access_modifier);
+            open_options.access(access_modifier.0);
         }
         let Ok(key_python) = open_options.open(r"Software\Python") else {
             continue;
@@ -131,7 +128,7 @@ pub enum ManagedPep514Error {
     #[error("Windows has an unknown pointer width for arch: `{_0}`")]
     InvalidPointerSize(Arch),
     #[error("Failed to write registry entry: {0}")]
-    WriteError(#[from] windows_result::Error),
+    WriteError(#[from] windows::core::Error),
 }
 
 /// Register a managed Python installation in the Windows registry following PEP 514.
@@ -216,7 +213,7 @@ pub fn remove_registry_entry<'a>(
     if all {
         debug!("Removing registry key HKCU:\\{}", astral_key);
         if let Err(err) = CURRENT_USER.remove_tree(&astral_key) {
-            if err.code() == ERROR_NOT_FOUND {
+            if err.code() == HRESULT::from(ERROR_FILE_NOT_FOUND) {
                 debug!("No registry entries to remove, no registry key {astral_key}");
             } else {
                 warn_user!("Failed to clear registry entries under {astral_key}: {err}");
@@ -230,7 +227,7 @@ pub fn remove_registry_entry<'a>(
         let python_entry = format!("{astral_key}\\{python_tag}");
         debug!("Removing registry key HKCU:\\{}", python_entry);
         if let Err(err) = CURRENT_USER.remove_tree(&python_entry) {
-            if err.code() == ERROR_NOT_FOUND {
+            if err.code() == HRESULT::from(ERROR_FILE_NOT_FOUND) {
                 debug!(
                     "No registry entries to remove for {}, no registry key {}",
                     installation.key(),
@@ -256,7 +253,7 @@ pub fn remove_orphan_registry_entries(installations: &[ManagedPythonInstallation
     let astral_key = format!("Software\\Python\\{COMPANY_KEY}");
     let key = match CURRENT_USER.open(&astral_key) {
         Ok(subkeys) => subkeys,
-        Err(err) if err.code() == ERROR_NOT_FOUND => {
+        Err(err) if err.code() == HRESULT::from(ERROR_FILE_NOT_FOUND) => {
             return;
         }
         Err(err) => {
@@ -268,7 +265,7 @@ pub fn remove_orphan_registry_entries(installations: &[ManagedPythonInstallation
     // Separate assignment since `keys()` creates a borrow.
     let subkeys = match key.keys() {
         Ok(subkeys) => subkeys,
-        Err(err) if err.code() == ERROR_NOT_FOUND => {
+        Err(err) if err.code() == HRESULT::from(ERROR_FILE_NOT_FOUND) => {
             return;
         }
         Err(err) => {
@@ -284,7 +281,7 @@ pub fn remove_orphan_registry_entries(installations: &[ManagedPythonInstallation
         let python_entry = format!("{astral_key}\\{subkey}");
         debug!("Removing orphan registry key HKCU:\\{}", python_entry);
         if let Err(err) = CURRENT_USER.remove_tree(&python_entry) {
-            if err.code() == ERROR_NOT_FOUND {
+            if err.code() == HRESULT::from(ERROR_FILE_NOT_FOUND) {
                 continue;
             }
             // TODO(konsti): We don't have an installation key here.
diff --git a/crates/uv-shell/Cargo.toml b/crates/uv-shell/Cargo.toml
index f70fffa00..bba5976b9 100644
--- a/crates/uv-shell/Cargo.toml
+++ b/crates/uv-shell/Cargo.toml
@@ -24,9 +24,8 @@ tracing = { workspace = true }
 nix = { workspace = true }
 
 [target.'cfg(windows)'.dependencies]
+windows = { workspace = true }
 windows-registry = { workspace = true }
-windows-result = { workspace = true }
-windows-sys = { workspace = true }
 
 [dev-dependencies]
 fs-err = { workspace = true }
diff --git a/crates/uv-shell/src/windows.rs b/crates/uv-shell/src/windows.rs
index 00c46eb79..818d5b999 100644
--- a/crates/uv-shell/src/windows.rs
+++ b/crates/uv-shell/src/windows.rs
@@ -8,9 +8,9 @@ use std::path::Path;
 
 use anyhow::Context;
 use tracing::warn;
+use windows::Win32::Foundation::{ERROR_FILE_NOT_FOUND, ERROR_INVALID_DATA};
+use windows::core::HRESULT;
 use windows_registry::{CURRENT_USER, HSTRING};
-use windows_result::HRESULT;
-use windows_sys::Win32::Foundation::{ERROR_FILE_NOT_FOUND, ERROR_INVALID_DATA};
 
 use uv_static::EnvVars;
 
@@ -60,13 +60,11 @@ fn get_windows_path_var() -> anyhow::Result<Option<HSTRING>> {
     let reg_value = environment.get_hstring(EnvVars::PATH);
     match reg_value {
         Ok(reg_value) => Ok(Some(reg_value)),
-        Err(err) if err.code() == HRESULT::from_win32(ERROR_INVALID_DATA) => {
+        Err(err) if err.code() == HRESULT::from(ERROR_INVALID_DATA) => {
             warn!("`HKEY_CURRENT_USER\\Environment\\PATH` is a non-string");
             Ok(None)
         }
-        Err(err) if err.code() == HRESULT::from_win32(ERROR_FILE_NOT_FOUND) => {
-            Ok(Some(HSTRING::new()))
-        }
+        Err(err) if err.code() == HRESULT::from(ERROR_FILE_NOT_FOUND) => Ok(Some(HSTRING::new())),
         Err(err) => Err(err.into()),
     }
 }
diff --git a/crates/uv/Cargo.toml b/crates/uv/Cargo.toml
index 0a83fa176..e0b145d22 100644
--- a/crates/uv/Cargo.toml
+++ b/crates/uv/Cargo.toml
@@ -119,7 +119,6 @@ zip = { workspace = true }
 arrayvec = { workspace = true }
 self-replace = { workspace = true }
 windows = { workspace = true }
-windows-result = { workspace = true }
 
 [dev-dependencies]
 assert_cmd = { workspace = true }
diff --git a/crates/uv/src/windows_exception.rs b/crates/uv/src/windows_exception.rs
index 048eaa1ba..8784793c1 100644
--- a/crates/uv/src/windows_exception.rs
+++ b/crates/uv/src/windows_exception.rs
@@ -54,11 +54,11 @@ enum ExceptionSafeStderr {
 }
 
 impl ExceptionSafeStderr {
-    fn new() -> Result<Self, windows_result::Error> {
+    fn new() -> Result<Self, windows::core::Error> {
         // SAFETY: winapi call, no interesting parameters
         let handle = unsafe { GetStdHandle(STD_ERROR_HANDLE) }?;
         if handle.is_invalid() {
-            return Err(windows_result::Error::empty());
+            return Err(windows::core::Error::empty());
         }
         let mut mode = CONSOLE_MODE::default();
         // SAFETY: winapi calls, no interesting parameters
@@ -73,7 +73,7 @@ impl ExceptionSafeStderr {
         }
     }
 
-    fn write_winerror(&mut self, s: &str) -> Result<(), windows_result::Error> {
+    fn write_winerror(&mut self, s: &str) -> Result<(), windows::core::Error> {
         match self {
             Self::WriteConsole(handle) => {
                 // According to comments in the ReactOS source, NT's behavior is that writes of 80