diff --git a/crates/uv/tests/it/python_module.rs b/crates/uv/tests/it/python_module.rs
index 06545ffd0..316dbe237 100644
--- a/crates/uv/tests/it/python_module.rs
+++ b/crates/uv/tests/it/python_module.rs
@@ -143,7 +143,7 @@ fn find_uv_bin_prefix() {
     ----- stderr -----
     Traceback (most recent call last):
       File "<string>", line 1, in <module>
-      File "[TEMP_DIR]/prefix/[PYTHON-LIB]/site-packages/uv/_find_uv.py", line 36, in find_uv_bin
+      File "[TEMP_DIR]/prefix/[PYTHON-LIB]/site-packages/uv/_find_uv.py", line 37, in find_uv_bin
         raise FileNotFoundError(path)
     FileNotFoundError: [USER_SCHEME]/[BIN]/uv
     "#
@@ -187,18 +187,14 @@ fn find_uv_bin_base_prefix() {
     uv_snapshot!(context.filters(), context.python_command()
         .arg("-c")
         .arg(format!(r#"import sys, uv; sys.base_prefix = "{}"; print(uv.find_uv_bin())"#, base_venv.path().portable_display()))
-        .env(EnvVars::PYTHONPATH, site_packages_path(base_venv.path(), "python3.12")), @r#"
-    success: false
-    exit_code: 1
+        .env(EnvVars::PYTHONPATH, site_packages_path(base_venv.path(), "python3.12")), @r"
+    success: true
+    exit_code: 0
     ----- stdout -----
+    [TEMP_DIR]/base-venv/[BIN]/uv
 
     ----- stderr -----
-    Traceback (most recent call last):
-      File "<string>", line 1, in <module>
-      File "[TEMP_DIR]/base-venv/[PYTHON-LIB]/site-packages/uv/_find_uv.py", line 36, in find_uv_bin
-        raise FileNotFoundError(path)
-    FileNotFoundError: [USER_SCHEME]/[BIN]/uv
-    "#
+    "
     );
 }
 
@@ -241,7 +237,7 @@ fn find_uv_bin_in_ephemeral_environment() -> anyhow::Result<()> {
      + uv==0.1.0 (from file://[WORKSPACE]/scripts/packages/fake-uv)
     Traceback (most recent call last):
       File "<string>", line 1, in <module>
-      File "[CACHE_DIR]/archive-v0/[HASH]/[PYTHON-LIB]/site-packages/uv/_find_uv.py", line 36, in find_uv_bin
+      File "[CACHE_DIR]/archive-v0/[HASH]/[PYTHON-LIB]/site-packages/uv/_find_uv.py", line 37, in find_uv_bin
         raise FileNotFoundError(path)
     FileNotFoundError: [USER_SCHEME]/[BIN]/uv
     "#
@@ -299,7 +295,7 @@ fn find_uv_bin_in_parent_of_ephemeral_environment() -> anyhow::Result<()> {
      + sniffio==1.3.1
     Traceback (most recent call last):
       File "<string>", line 1, in <module>
-      File "[SITE_PACKAGES]/uv/_find_uv.py", line 36, in find_uv_bin
+      File "[SITE_PACKAGES]/uv/_find_uv.py", line 37, in find_uv_bin
         raise FileNotFoundError(path)
     FileNotFoundError: [USER_SCHEME]/[BIN]/uv
     "#
diff --git a/python/uv/_find_uv.py b/python/uv/_find_uv.py
index 00b7d8873..0c45aff1a 100644
--- a/python/uv/_find_uv.py
+++ b/python/uv/_find_uv.py
@@ -10,20 +10,21 @@ def find_uv_bin() -> str:
 
     uv_exe = "uv" + sysconfig.get_config_var("EXE")
 
+    # Search in the scripts directory for the current prefix
     path = os.path.join(sysconfig.get_path("scripts"), uv_exe)
     if os.path.isfile(path):
         return path
 
-    if sys.version_info >= (3, 10):
-        user_scheme = sysconfig.get_preferred_scheme("user")
-    elif os.name == "nt":
-        user_scheme = "nt_user"
-    elif sys.platform == "darwin" and sys._framework:
-        user_scheme = "osx_framework_user"
-    else:
-        user_scheme = "posix_user"
+    # If in a virtual environment, also search in the base prefix's scripts directory
+    if sys.prefix != sys.base_prefix:
+        path = os.path.join(
+            sysconfig.get_path("scripts", vars={"base": sys.base_prefix}), uv_exe
+        )
+        if os.path.isfile(path):
+            return path
 
-    path = os.path.join(sysconfig.get_path("scripts", scheme=user_scheme), uv_exe)
+    # Search in the user scheme scripts directory, e.g., `~/.local/bin`
+    path = os.path.join(sysconfig.get_path("scripts", scheme=_user_scheme()), uv_exe)
     if os.path.isfile(path):
         return path
 
@@ -34,3 +35,15 @@ def find_uv_bin() -> str:
         return target_path
 
     raise FileNotFoundError(path)
+
+
+def _user_scheme() -> str:
+    if sys.version_info >= (3, 10):
+        user_scheme = sysconfig.get_preferred_scheme("user")
+    elif os.name == "nt":
+        user_scheme = "nt_user"
+    elif sys.platform == "darwin" and sys._framework:
+        user_scheme = "osx_framework_user"
+    else:
+        user_scheme = "posix_user"
+    return user_scheme